Search results for "Sideritis leucantha"

showing 2 items of 2 documents

Anti-Inflammatory Activity of a Flavone from Sideritis leucantha.

1986

PharmacologyTraditional medicinemedicine.drug_classOrganic ChemistryPharmaceutical ScienceBiologybiology.organism_classificationAnti-inflammatoryAnalytical ChemistryComplementary and alternative medicineDrug DiscoverymedicineMolecular MedicineSideritis leucanthaPlanta medica
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Studies on the gastric anti-ulcer activity of hypolaetin-8-glucoside

1988

The gastric anti-ulcer activity of hypolaetin-8-O-β-D-glucoside (H-8-G), a flavonoid isolated from Sideritis leucantha, has been studied in rats. This compound significantly reduced gastric lesions induced by ethanol or acetylsalicylic acid (ASA), with an increase in mucus production. In the pylorus-ligated rat, H-8-G did not affect the volume of gastric secretion but decreased its acidity and peptic activity. The anti-ulcer activity of this flavonoid does not depend on stimulation of cell proliferation in the rat gastric mucosa. Our results suggest that H-8-G activity is related to its cytoprotective effects [mediated by endogenous prostaglandins (PGs) and associated to an increase in gast…

Pharmacologychemistry.chemical_classificationEthanolbiologyCell growthPepticdigestive oral and skin physiologyFlavonoidStimulationEndogenyPharmacologybiology.organism_classificationdigestive system diseaseschemistry.chemical_compoundmedicine.anatomical_structurechemistryBiochemistryGastric mucosamedicineSideritis leucanthaPhytotherapy Research
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